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Warthin's tumor as a hamartomatous dysplastic lesion: a histochemical and immunohistochemical study

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dc.contributor.authorTakaaki Ohmories
dc.contributor.authorUraga, Naomies
dc.contributor.authorTabei, Ryo
dc.date.accessioned2011-02-01T08:46:18Z
dc.date.available2011-02-01T08:46:18Z
dc.date.issued1991
dc.description.abstractThe etiology of Warthin's tumor was sought by histochemical and immunohistochemical methods using 7 surgically extirpated samples and normal salivary glands as a control for the epithelial component. All the samples exhibited a variety of amyloid deposition in the interfollicular area of the lymphoid component. The interfollicular lymphoid cells were both T-cells and cells of B-cell lineage with an almost l to 2 population ratio. Most antigen-positive B-cells were plasma cells that exhibited polyclonality of irnmunoglobulin. B-cells were also present in the lymphoid mantles and a few were found in the germinal centres. The epithelial component exhibited mucinous and proteinaceous fluid in the lumen and varied immunohistological reactions; being particularly positive to carcinoembryonic antigen, S-100 protein, and B-cell antigen; quite similar to that of normal salivary duct cells. The results suggest that Warthin's tumor may not be a hamartomatous neoplasm at all but a hamartomatous dysplastic lesion.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18270
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectWarthin's tumores
dc.subjectSalivary glandes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleWarthin's tumor as a hamartomatous dysplastic lesion: a histochemical and immunohistochemical studyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 6, nº 4 (1991)