Publication: Inflammation and infection in Parkinson`s disease
Authors
Arai, H. ; Furuya, T. ; Mizuno, Y. ; Mochizuki, H.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The hallmark of Parkinson’s disease (PD) is
a specific degeneration of dopaminergic neurons in the
substantia nigra (SN). The cause of nigral dopaminergic
neuronal cell death in PD and its underlying mechanisms
remain elusive, however, involvement of inflammatory
events has been postulated because inflammatory
features have been described in the brain of PD patients.
Some evidence also suggest that a possible deleterious
effects of neuroinflammatory processes by infection in
experimental models of neurodegenerative disease. In
this review, we summarize and discuss the latest findings
regarding inflammation in PD. Especially, we focused
on the relationship between infection and PD.
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Citation
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