Ultrasound-assisted enzymatic synthesis of xylitol fatty acid esters in
solvent-free conditions

Donaire, Antonio; Villa Aroca, Rocío; Lozano Rodríguez, Pedro; Nieto Cerón, Susana

Publication:
Ultrasound-assisted enzymatic synthesis of xylitol fatty acid esters in solvent-free conditions

dc.contributor.author	Donaire, Antonio
dc.contributor.author	Villa Aroca, Rocío
dc.contributor.author	Lozano Rodríguez, Pedro
dc.contributor.author	Nieto Cerón, Susana
dc.contributor.department	Bioquímica y Biología Molecular B e Inmunología
dc.date.accessioned	2025-01-09T17:33:16Z
dc.date.available	2025-01-09T17:33:16Z
dc.date.issued	2021-07
dc.description	© 2021 The Author(s). This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Published Manuscript version of a Published Work that appeared in final form in Ultrasonics Sonochemistry. To access the final edited and published work see https://doi.org/10.1016/j.ultsonch.2021.105606
dc.description.abstract	A commercial immobilized lipase was successfully used for the synthesis of five xylityl acyl esters by means of the esterification of free fatty acids (caprylic, capric, lauric and myristic, respectively) with xylitol under solvent-free conditions. Ultrasound-assistance was shown to be a key tool to overcome the handicap imposed by both the mutual immiscibility of fatty acids and xylitol substrates, and the semisolid character of the initial reaction mixtures. In such semisolid systems, ultrasonic irradiation may enable the transport of substrate molecules to the enzyme catalytic-site, leading to the efficient synthesis of xylityl fatty ester (e.g. up to 95% yield after 90 min at 40ºC), with xylityl monoacyl ester and xylitol diacyl ester appearing as the main products (>96%), assessed by HPLC and NMR analyses. The separation of products was carried out by heating and simple centrifugation of the reaction medium, which was possible due to different densities of the resulting fractions.	es
dc.format	application/pdf	es
dc.format.extent	8	es
dc.identifier.citation	Ultrasonics Sonochemistry, 2021, Vol. 75 : 105606
dc.identifier.doi	https://doi.org/10.1016/j.ultsonch.2021.105606
dc.identifier.issn	Print: 1350-4177
dc.identifier.issn	Electronic: 1873-2828
dc.identifier.uri	http://hdl.handle.net/10201/148183
dc.language	eng	es
dc.publisher	Elsevier	º
dc.relation	This work was partially supported by RTI2018-098233-B-C21 (MICINN-FEDER), and 20790/PI/18 (Fundación SENECA-CARM).	es
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S1350417721001486?via%3Dihub
dc.rights	info:eu-repo/semantics/openAccess	es
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Xylitol fatty acid esters	es
dc.subject	Solvent free systems
dc.subject	Biocatalysis
dc.subject	Ultrasound assistance
dc.subject	Biosurfactants
dc.title	Ultrasound-assisted enzymatic synthesis of xylitol fatty acid esters in solvent-free conditions	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es
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