Publication: Pathological changes of human unmyelinated nerve fibers: a review
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Date
2000
Authors
Kanda, T.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
In the cutaneous nerves, unmyelinated nerve
fibers outnumber the myelinated ones but are scarcely
analyzed, especially at autopsy. This indifference toward
the pathology of unmyelinated nerve fibers may be due
to the necessity of electron microscopic analyses and,
more importantly, the obscurity of pathological
alteration of unmyelinated nerve fibers in aging as well
as in peripheral nerve disorders. The aim of this article is
to review (1) the normal appearance including postmortem
changes, (2) the age-related changes, and (3) the
pathological alteration in various neuropathic and nonneuropathic
conditions, of unmyelinated nerve fibers in
the sural nerve. For the complete analyses of sural nerve,
qualitative and quantitative estimation of unmyelinated
nerve fibers in all specimens should be recommended
and it sometimes has an important diagnostic value
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