Publication: Clinicopathological characteristics and prognosis of Chinese patients with
sarcomatoid carcinoma of the bladder
Authors
Guo, Ai T. ; Huang, Heng ; We, Li X.
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Publisher
F. Hernández y Juan F. Madrid. Universidad de Murcia. Departamento de Biología Celular e Histología
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Objectives: The purpose of this study was to
retrospectively analyze the clinicopathological features
and prognosis of Chinese patients diagnosed with
sarcomatoid carcinoma (SC) of the bladder.
Methods: 13 patients admitted to the General
Hospital of People’s Liberation Army (PLA) between
1999 and 2010 (study group) and 74 Chinese patients
diagnosed between 1994 and 2010 and reported in one
of two Chinese databases (literature group).
Results: The two groups were similar in all
demographic and clinical characteristics except depth of
tumor invasion. SC of the bladder was most common in
older males and most patients had high-grade or latestage
disease at diagnosis. The 6-month, 1-year, 2-year,
and 5-years survival rates were 78.9%, 42.7%, 28.0%,
and 21.0%, respectively. Analysis of the association of
demographic and clinical characteristics with prognosis
indicated no significant effect of sex, age, lesion
location, tumor diameter, tumor type, depth of invasion,
type of surgery, gross hematuria, and urinary tract
infection.
Conclusions: Our results suggest that the pathologic
tumor stage was unrelated to prognosis. Early diagnosis
and surgical intervention are preferred strategies for
improvement of prognosis. The association between
clinical stage and survival time requires further analysis.
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Citation
Histology and Histopathology, vol. 28, nº 9 (2013)
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