Publication:
Potential influence of prenatal 2.45 GHz radiofrequency electromagnetic field exposure on Wistar albino rat testis

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dc.contributor.authorAlmášiová, Viera
dc.contributor.authorHolovská, Katarína
dc.contributor.authorAndrašková, Sandra
dc.contributor.authorCigánková, Viera
dc.contributor.authorŠevčíková, Zuzana
dc.contributor.authorRaček, Adam
dc.contributor.authorAndrejčáková, Zuzana
dc.contributor.authorTóth, Štefan
dc.contributor.authorTvrdá, Eva
dc.contributor.authorMolnár, Ján
dc.contributor.authorRačeková, Enikö
dc.date.accessioned2023-01-18T11:57:13Z
dc.date.available2023-01-18T11:57:13Z
dc.date.issued2021
dc.description.abstractAn ever-increasing use of wireless devices over the last decades has forced scientists to clarify their impact on living systems. Since prenatal development is highly sensitive to numerous noxious agents, including radiation, we focused on the assessment of potential adverse effects of microwave radiation (MR) on testicular development. Pregnant Wistar albino rats (3 months old, weighing 282±8 g) were exposed to pulsed MR at a frequency of 2.45 GHz, mean power density of 2.8 mW/cm2, and a specific absorption rate of 1.82 W/kg for 2 hours/day throughout pregnancy. Male offspring were no longer exposed to MR following birth. Samples of biological material were collected after reaching adulthood (75 days). In utero MR exposure caused degenerative changes in the testicular parenchyma of adult rats. The shape of the seminiferous tubules was irregular, germ cells were degenerated and often desquamated. The diameters of the seminiferous tubules and the height of the germinal epithelium were significantly decreased (both at **p<0.01), while the interstitial space was significantly increased (**p<0.01) when compared to the controls. In the group of rats prenatally exposed to MR, the somatic and germ cells were rich in vacuoles and their organelles were often altered. Necrotizing cells were more frequent and empty spaces between Sertoli cells and germ cells were observed. The Leydig cells contained more lipid droplets. An increased Fluoro Jade - C and superoxide dismutase 2 positivity was detected in the rats exposed to MR. Our results confirmed adverse effects of MR on testicular development.es
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dc.format.extent12es
dc.identifier.citationHistology and Histopathology Vol. 36, nº6 (2021)
dc.identifier.doihttps://doi.org/10.14670/HH-18-331
dc.identifier.issn0213-3911
dc.identifier.issn1699-5848
dc.identifier.urihttp://hdl.handle.net/10201/127485
dc.languageenges
dc.publisherUniversidad de Murcia, Departamento de Biologia Celular e Histiologiaes
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectRatses
dc.subjectFetal developmentes
dc.subjectMicrowaveses
dc.subjectTesteses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titlePotential influence of prenatal 2.45 GHz radiofrequency electromagnetic field exposure on Wistar albino rat testises
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.36, nº6 (2021)