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Effect of in vitro gastrointestinal digestion on encapsulated and nonencapsulated phenolic compounds of Carob (Ceratonia siliqua L.) pulp extracts and their antioxidant capacity

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dc.contributor.authorYdjedd, Siham
dc.contributor.authorBouriche, Sihem
dc.contributor.authorLópez Nicolás, Rubén
dc.contributor.authorSánchez Moya, Teresa
dc.contributor.authorFrontela Saseta, María del Carmen
dc.contributor.authorRos Berruezo, Gaspar
dc.contributor.authorRezgu, Farouk
dc.contributor.authorLouaileche, Hayette
dc.contributor.authorKati, Djamel-Edine
dc.contributor.departmentTecnología de Alimentos, Nutrición y Bromatología
dc.contributor.otherFacultad de Veterinaria
dc.date.accessioned2026-01-26T09:08:15Z
dc.date.available2026-01-26T09:08:15Z
dc.date.copyright© 2017, American Chemical Society
dc.date.issued2017-01-17
dc.description.abstractTo determine the effect of in vitro gastrointestinal digestion on the release and antioxidant capacity of encapsulated and nonencapsulated phenolics carob pulp extracts, unripe and ripe carob pulp extracts were microencapsulated with polycaprolactone via double emulsion/solvent evaporation technique. Microcapsules' characterization was performed using scanning electron microscopy and Fourier transform infrared spectrometry analysis. Total phenolics and flavonoids content and antioxidant activities (ORAC, DPPH, and FRAP) were evaluated after each digestion step. The release of phenolic acids and flavonoids was measured along the digestion process by HPLC-MS/MS analysis. The most important phenolics and flavonoids content as well as antioxidant activities were observed after gastric and intestinal phases for nonencapsulated and encapsulated extracts, respectively. The microencapsulation of carob polyphenols showed a protective effect against pH changes and enzymatic activities along digestion, thereby promoting a controlled release and targeted delivery of the encapsulated compound, which contributed to an increase in its bioaccessibility in the gut.
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dc.identifier.citationYdjedd S, Bouriche S, López-Nicolás R, Sánchez-Moya T, Frontela-Saseta C, Ros-Berruezo G, Rezgui F, Louaileche H, Kati DE. Effect of in Vitro Gastrointestinal Digestion on Encapsulated and Nonencapsulated Phenolic Compounds of Carob (Ceratonia siliqua L.) Pulp Extracts and Their Antioxidant Capacity. J Agric Food Chem. 2017 Feb 1;65(4):827-835. doi: 10.1021/acs.jafc.6b05103. Epub 2017 Jan 17. PMID: 28094929.
dc.identifier.doihttps://doi.org/10.1021/acs.jafc.6b05103
dc.identifier.eissn1520-5118
dc.identifier.issn0021-8561
dc.identifier.urihttp://hdl.handle.net/10201/193569
dc.languageeng
dc.publisherAmerican Chemical Society
dc.relationÁmbito internacional: financial support of the Algerian Ministry of Higher Education Ámbito nacional: Ministerio de Economıá y Competitividad (Spain) through the Project AGL2016-78125-R.
dc.relation.publisherversionhttps://pubs.acs.org/doi/10.1021/acs.jafc.6b05103
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.odsObjetivo 3: Salud
dc.titleEffect of in vitro gastrointestinal digestion on encapsulated and nonencapsulated phenolic compounds of Carob (Ceratonia siliqua L.) pulp extracts and their antioxidant capacity
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
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