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Studies on the breakdown of glycogen in the lysosomes: The effects of hydrocortisone

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dc.contributor.authorKalamidas, Stefanoses
dc.contributor.authorKotoulas, Othon B.es
dc.date.accessioned2011-02-22T11:20:12Z
dc.date.available2011-02-22T11:20:12Z
dc.date.issued2000
dc.description.abstractThe effects of hydrocortisone on newborn rat liver were studied by using biochemical assays, electron microscopy and quantitative morphometry. Hydrocortisone increased the number of lysosomes in the hepatocytes. Most of the lysosomes represented glycogen-containing autophagic vacuoles. The glucocorticoid also increased the activity of the liver glycogen-hydrolyzing acid glucosidase and the breakdown of glycogen inside lysosomes. The activity of the liver acid mannose 6-phosphatase was decreased. This may be related to the stimulation of autophagic mechanisms in the newborn rat hepatocyteses
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/19281
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectHydrocortisonees
dc.subjectLysosomeses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiologíaes
dc.titleStudies on the breakdown of glycogen in the lysosomes: The effects of hydrocortisonees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.15, nº 1 (2000)