Biochemical correction factors to estimation of post-mortem interval in vitreous humor

Prieto Bonete, Gemma; Pérez Martínez, Cristina; Pérez Cárceles, María Dolores; Luna, Aurelio; Legaz Pérez, Isabel

Publication:
Biochemical correction factors to estimation of post-mortem interval in vitreous humor

dc.contributor.author	Prieto Bonete, Gemma
dc.contributor.author	Pérez Martínez, Cristina
dc.contributor.author	Pérez Cárceles, María Dolores
dc.contributor.author	Luna, Aurelio
dc.contributor.author	Legaz Pérez, Isabel
dc.contributor.department	Ciencias Sociosanitarias
dc.date.accessioned	2024-07-12T10:45:40Z
dc.date.available	2024-07-12T10:45:40Z
dc.date.issued	2017
dc.description	© 2017 Romanian Society of Legal Medicine. This document is the Published version of a Published Work that appeared in final form in Romanian Journal of Legal Medicine. To access the final edited and published work see https://doi.org/10.4323/rjlm.2017.201
dc.description.abstract	Vitreous humor is the matrix chosen on most occasions because it is less likely to be affected by postmortem changes. Potassium concentration is the common measurement of estimation time since death in vitreous humor, but there are another electrolytes concentrations are stable after death. The aim of this study was to analyze whether any of the components or characteristics of VH can be use as inner standard in a postmortem interval of less than 24 hours to accurately estimate the time of death in both natural and violent death. A total of 298 vitreous humor from 298 different cadavers (204 males, 94 females) with a mean age of 19.9 ± 13.31 (hours ± SD) and different causes of death (myocardial infarction, multiple injuries, suffocation or intoxication).The concentrations of potassium, phosphate, hypoxanthine, uric acid, microproteins, microalbumine, chloride, sodium were determined. After measurement, we observed that chloride, sodium, urea and osmotic pressure were independent of the PMI. Our results show that sodium concentration is the best inner standard to have a accurate estimation of post-mortem interval and it can give information about disturbed electrolyte homeostasis at the moment of death.	es
dc.format	application/pdf	es
dc.format.extent	4	es
dc.identifier.citation	Rom J Leg Med [25] 201-204 [2017]
dc.identifier.doi	https://doi.org/10.4323/rjlm.2017.201
dc.identifier.issn	Print: 1221-8618
dc.identifier.issn	Electronic: 1844-8585
dc.identifier.uri	http://hdl.handle.net/10201/143066
dc.language	eng	es
dc.publisher	Romanian Society of Legal Medicine
dc.relation	Sin financiación externa a la Universidad	es
dc.relation.publisherversion	https://www.rjlm.ro/index.php/arhiv/562
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject	Forensic medicine	es
dc.subject	Vitreous humor	es
dc.subject	Inner standard	es
dc.subject	Stable electrolytes	es
dc.subject	Post-mortem interval	es
dc.title	Biochemical correction factors to estimation of post-mortem interval in vitreous humor	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es
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