Long-term study of physical, haematological and biochemical parameters in cattle with different embryo origins

Serrano-Albal, Maria; Canovas, Sebastian; Heras, Sonia; Gadea, Joaquin; Coy, Pilar; Romar, Raquel; Romero Aguirregomezcorta, Jon

Publication:
Long-term study of physical, haematological and biochemical parameters in cattle with different embryo origins

dc.contributor.author	Serrano-Albal, Maria
dc.contributor.author	Canovas, Sebastian
dc.contributor.author	Heras, Sonia
dc.contributor.author	Gadea, Joaquin
dc.contributor.author	Coy, Pilar
dc.contributor.author	Romar, Raquel
dc.contributor.author	Romero Aguirregomezcorta, Jon
dc.contributor.department	Fisiología	es
dc.date.accessioned	2025-09-04T07:15:55Z
dc.date.available	2025-09-04T07:15:55Z
dc.date.copyright	© 2025 by the authors
dc.date.issued	2025-06-14
dc.description.abstract	Assisted reproductive technologies are vital in cattle breeding to improve genetic selection and productivity. While early-life differences between artificially inseminated (AI) and in vitro-produced (IVP) cattle have been studied, long-term physiological, haematological, and biochemical effects remain unclear. This observational study assessed AI and IVP cattle from 1.5 to 5 years of age to determine if early differences persist. IVP cattle were produced after the transfer of the embryo produced by supplementing (RF-IVP group) or not supplementing (C-IVP) the embryo culture with oviductal and uterine fluids. Physical evaluations showed body mass index increased until 3.5 years, while temperature and respiratory rate declined with age, with no significant differences between AI and IVP groups. Haematological analysis revealed age-related changes, including decreased red and white blood cell counts and increased mean corpuscular volume and haemoglobin. AI cattle had higher white blood cell counts than IVP groups. Sex significantly influenced many haematological variables. Biochemical analysis showed age-related increases in total protein, creatinine, and urea, and decreases in glucose and alkaline phosphatase. AI cattle had lower cholesterol and creatinine than IVP groups. Despite group differences, all values remained within normal ranges. Sex affected albumin, cholesterol, triglycerides, and creatine kinase. This study provides the first long-term haematological and biochemical reference values for cattle from different reproductive methods, showing that age is the main influencing factor and supporting IVP cattle as a viable alternative to AI in breeding programs.	es
dc.format	application/pdf	es
dc.format.extent	17	es
dc.identifier.citation	Animals 2025, 15, 1763
dc.identifier.doi	https://doi.org/10.3390/ani15121763
dc.identifier.issn	Electronic: 2076-2615
dc.identifier.uri	http://hdl.handle.net/10201/158144
dc.language	eng	es
dc.publisher	MDPI	es
dc.relation	This research is part of project PID2020-113366RB-I00 funded by Ministerio de Ciencia e Innovación-Agencia Estatal de Investigacón MCIN/AEI/10.13039/501100011033/ and “FEDER Una manera de hacer Europa”. SH was funded by Juan de la Cierva-Incorporación IJC2019-039404-I (MCIN/AEI/10.13039/501100011033).	es
dc.relation.ispartof	PhenotypART -- Phenotypic and genetic characterization of livestock animals derived from assisted reproductive technologies	es
dc.relation.publisherversion	https://www.mdpi.com/2076-2615/15/12/1763	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.rights	Attribution 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	*
dc.subject	Assisted reproductive technologies	es
dc.subject	Cattle	es
dc.subject	Haematologial profile	es
dc.subject	Biochemical profile	es
dc.subject	Long-term study	es
dc.title	Long-term study of physical, haematological and biochemical parameters in cattle with different embryo origins	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es
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relation.isAuthorOfPublication.latestForDiscovery	3cc83bb3-8c44-471d-bc14-7d7dff677509