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Lectins as differentiation markers of human gliomas

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dc.contributor.authorFigols, J.es
dc.contributor.authorCervós-Navarro, J.
dc.contributor.authorMadrid Cuevas, Juan Francisco
dc.date.accessioned2011-02-01T08:45:18Z
dc.date.available2011-02-01T08:45:18Z
dc.date.issued1991
dc.description.abstractThe lectins Concanavalin A (Con A). Ricinus communis agglutinin (RCA-1), Peanut agglutinin (PNA) and Wheat germ agglutinin (WGA) as well as the irnmunomarkers for glial fibrillary acidic protein (GFAP) and myelin basic protein (MBP) were used in a series of 21 glial turnors (4 pylocytic astrocytornas, 5 grade 11 astrocytornas, 3 anaplastic astrocytornas, 4 glioblastornas and 5 oligodendrogliornas). ConA binds to al1 tumoral astrocytes in low grade astrocytomas, as well as to well differentiated tumoral astrocytes in anaplastic astrocytomas and glioblastornas. RCA-1 has a similar behaviour. PNA, and to a lesser degree WGA, binds selectively to the oligodendroglial plasma membrane in well differentiated oligodendrogliomas. The results suggest that these lectins are markers of differentiation in gliomas rather than of malignancy.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18205
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectLectinses
dc.subjectGliomases
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.8 - Neurología. Neuropatología. Sistema nerviosoes
dc.titleLectins as differentiation markers of human gliomases
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
relation.isAuthorOfPublication773c85c2-1260-4a4d-9543-f5a615648d71
relation.isAuthorOfPublication.latestForDiscovery773c85c2-1260-4a4d-9543-f5a615648d71
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Histology and histopathology Vol. 6, nº 1 (1991)