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Impact of SARS-CoV-2 infection in patients with cystic fibrosis in Spain: Incidence and results of the national CF-COVID19-Spain survey

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dc.contributor.authorMondéjar López, Pedro Enrique
dc.contributor.authorQuintana-Gallego, Esther
dc.contributor.authorGirón-Moreno, Rosa M.
dc.contributor.authorCortell-Aznar, Isidoro
dc.contributor.authorBalbuena-Maiz, Marta Ruiz de
dc.contributor.authorDiab-Cáceres, Layla
dc.contributor.authorPrados-Sánchez, Concepción
dc.contributor.authorÁlvarez-Fernández, Antonio
dc.contributor.authorGarcía-Marcos, Patricia W.
dc.contributor.authorPeñalver Mellado, Carlos
dc.contributor.authorPastor-Vivero, M. Dolores
dc.contributor.authorOlveira, Casilda
dc.contributor.authorLópez-Neyra, Alejandro
dc.contributor.authorCastillo-Corullón, Silvia
dc.contributor.authorPalma-Milla, Samara
dc.contributor.authorPérez-Ruiz, Estela
dc.contributor.authorSole-Jover, Amparo
dc.contributor.authorBarrio, M. Isabel
dc.contributor.authorSánchez-Solís de Querol, Manuel
dc.contributor.authorAsensio de la Cruz, Óscar
dc.contributor.authorCF-COVID19-Spain Registry Group
dc.contributor.departmentCirugía, Pediatría y Obstetricia y Ginecología
dc.contributor.otherFacultad de Medicina
dc.date.accessioned2025-10-29T07:49:47Z
dc.date.available2025-10-29T07:49:47Z
dc.date.copyright© 2020 Elsevier Ltd.
dc.date.issued2020-06-08
dc.description.abstractBackground: Given the high incidence of confirmed infection by SARS-CoV-2 and mortality by COVID-19 in the Spanish population, its impact was analysed among persons with Cystic Fibrosis (CF) as a group at risk of a worse evolution. The possible causes of the incidence observed in them are explained and how CF Units have faced this health challenge is detailed. Methods: Retrospective descriptive observational study, for which a Spanish CF Patients with Confirmed COVID- 19 Registry is created, requesting information on number of people affected between 8 March–16 May 2020 and their clinical-demographic characteristics from the CF Units participating in the European Cystic Fibrosis Society Patient Registry (ECFSPR). The accumulated incidence is calculated, compared with that of the general population. Additionally, a survey (CF-COVID19-Spain) is carried out on prevention of SARS-CoV-2 infection, workings of CF Units and possible reasons for the incidence observed. Results: COVID-19 was diagnosed in eight CF patients, one of whom had received a lung transplant. The accu mulated incidence was 32/10000 in CF patients and 49/10000 in the general population. General death rate was 5.85/10000 while no CF patients included in the ECFSPR died. The characteristics of those affected and the results of the survey are described. Conclusions: Despite being considered a disease at high risk of severe COVID-19, the low incidence and mortality in CF patients in Spain contrasts with the figures for the general population. The possible factors that would explain such findings are discussed, with the help of the results of the CF-COVID19-Spain survey.
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dc.format.extent6
dc.identifier.citationRespiratory Medicine 170 (2020) 106062
dc.identifier.doihttps://doi.org/10.1016/j.rmed.2020.106062
dc.identifier.urihttp://hdl.handle.net/10201/169949
dc.languageeng
dc.relationSin financiación externa a la Universidad
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S095461112030202X?via%3Dihub
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectCystic fibrosis
dc.subjectSARS-CoV-2
dc.subjectCoronavirus
dc.subjectCOVID-19
dc.subject.odsObjetivo 3: Salud
dc.titleImpact of SARS-CoV-2 infection in patients with cystic fibrosis in Spain: Incidence and results of the national CF-COVID19-Spain survey
dc.typeinfo:eu-repo/semantics/article
dspace.entity.typePublicationes
relation.isAuthorOfPublicationfdb051d5-3185-4234-88b6-1cd4ce66e0d4
relation.isAuthorOfPublicationa20da46d-caef-436f-88c1-5ea0f45ce23e
relation.isAuthorOfPublication.latestForDiscoveryfdb051d5-3185-4234-88b6-1cd4ce66e0d4
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