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A new morphological classification during follow-up in patients with celiac disease. A three-dimensional observation by scanning electron microscopy

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dc.contributor.authorMagliocca, F.M.es
dc.contributor.authorBonamico, M.es
dc.contributor.authorPetrozza, V.
dc.contributor.authorMariani, P.
dc.contributor.authorCorrer, S.
dc.contributor.authorFamiliari, G.
dc.contributor.authorCarpino, F.
dc.date.accessioned2011-02-22T10:32:26Z
dc.date.available2011-02-22T10:32:26Z
dc.date.issued1996
dc.description.abstractThe structure and ultrastructure of the villi of small intestinal mucosa was examined in 237 duodenal or jejunal biopsies taken from children with active celiac disease and during gluten-free diet. Al1 biopsies were processed for light and scanning electron microscopy. Conventional histology showed four different morphological aspects: total and subtotal villous atrophy in patients on unrestricted diet, partial villous atrophy and normal mucosa during gluten-free diet. Scanning electron microscopy demonstrated that in active celiac disease the severity of the intestinal lesions was related to individual vulnerability to gluten. Our results showed that during dietary treatment the process of mucosa1 healing was constant and strictly time-dependent. Furthermore, the ultrastructural examination has been relevant in evaluating the evolution of the villous regeneration. In this study a classification regarding the healing process of the small intestinal mucosa correlated with the time of start of dietary therapy is proposed.es
dc.formatapplication/pdfes
dc.format.extent8es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18837
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectCeliac diseasees
dc.subjectUltrastructurees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleA new morphological classification during follow-up in patients with celiac disease. A three-dimensional observation by scanning electron microscopyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.11, nº 2 (1996)