Mammalian spermatogenesis investigated by genetic engineering

Publication:
Mammalian spermatogenesis investigated by genetic engineering

dc.contributor.author	Escalier, D.	es
dc.date.accessioned	2011-02-22T11:09:24Z
dc.date.available	2011-02-22T11:09:24Z
dc.date.issued	1999
dc.description.abstract	Genes involved in mammal spermatogenesis can now be identified through mutants created by genetic engineering. Information has been obtained on male meiosis, but also on the factors regulating the proliferation, maintenance and differentiation of male germ cells. Its has also increased our knowledge of the germ cell phenotype emerging from an altered germ cell genotype. This review is focused on data from genes expressed in male germ cells and on the question of how germ cells and Sertoli cells cope with the molecular lesions induced. The conservation of a wild-type phenotype of male germ cells in mutant mice is discussed, and how the mouse genetic background can lead to different germ cell phenotypes for a given gene mutation.	es
dc.format	application/pdf	es
dc.format.extent	14	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/19209
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Meiosis	es
dc.subject	Spermatogenesis	es
dc.subject.other	CDU::6 - Ciencias aplicadas::61 - Medicina	es
dc.title	Mammalian spermatogenesis investigated by genetic engineering	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

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