Heritability of sleep quality in a middle-aged twin sample from Spain

Gregory, Alice M.; Madrid Valero, Juan José; Martínez Selva, José María; Ordoñana Martín, Juan Ramón; Sánchez Romera, Juan Francisco

Publication:
Heritability of sleep quality in a middle-aged twin sample from Spain

dc.contributor.author	Gregory, Alice M.
dc.contributor.author	Madrid Valero, Juan José
dc.contributor.author	Martínez Selva, José María
dc.contributor.author	Ordoñana Martín, Juan Ramón
dc.contributor.author	Sánchez Romera, Juan Francisco
dc.contributor.department	Anatomía Humana y Psicobiología
dc.date.accessioned	2024-01-17T09:40:48Z
dc.date.available	2024-01-17T09:40:48Z
dc.date.created	2018
dc.date.issued	2018
dc.description	©2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Accepted version of a Published Work that appeared in final form in Sleep. To access the final edited and published work see https://doi.org/10.1093/sleep/zsy110	es
dc.description.abstract	Study objectives: Sleep quality is associated with health throughout the life span, which is particularly salient in middle-age and older adulthood. Sleep quality appears to be influenced by both genetic and environmental factors. However, there is still limited information about genetic influences on sleep quality in middle-aged adults, and particularly in those from certain geographical locations. We estimated the magnitude of genetic and environmental influences on sleep quality in a representative sample of middle-aged Spanish twins. Methods: The sample comprised 2150 individuals born between 1939 and 1966, who participate in the Murcia Twin Registry. In order to estimate the heritability of sleep quality variables we performed univariate analyses for the global score on the Pittsburgh sleep quality index and for each of its components. Results: We found moderate but significant heritability (34%) for sleep quality. The genetic variance of the components of the Pittsburgh index ranged from 30% to 45%, except for sleep efficiency for which no genetic influence could be detected. In summary, there was a moderate genetic influence on most dimensions of sleep quality in a sample of adult male and female twins. Shared environment influences were not found. Conclusions: This study adds new information regarding the underlying determinants of sleep quality by providing heritability estimates in a middle-aged population-based representative sample from a geographical location that has not been included in studies of this type previously. This could provide a reference point for future research regarding sleep research in middle-age.	es
dc.format	application/pdf	es
dc.format.extent	20	es
dc.identifier.doi	https://doi.org/10.1093/sleep/zsy110
dc.identifier.eisbn	Sleep. 2018 Sep 1;41(9) ISSN:1550-9109	es
dc.identifier.uri	http://hdl.handle.net/10201/137335
dc.language	eng	es
dc.relation	Financiación: Fundación Séneca, Regional Agency for Science and Technology of the Murcia Region (Projects 15302 / PHCS /10; and 19479 / PI / 14) and the Ministry of Economy and Competitiveness (PSI2009-11560 and PSI2014-56680-R). Author JJMV is supported by pre-doctoral scholarship (19814/FPI/15) of the Fundación Séneca.	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Adult	es
dc.subject	Dizygotic	es
dc.subject	Heritability	es
dc.subject	Monozygotic	es
dc.subject	Sleep duration	es
dc.subject	Sleep quality	es
dc.subject	Twins.	es
dc.subject.other	CDU::1 - Filosofía y psicología	es
dc.title	Heritability of sleep quality in a middle-aged twin sample from Spain	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es
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