Publication:
Macrophages in rheumatoid arthritis

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Authors
Maruotti, Nicola ; Cantatore, F.P. ; Crivellato, E. ; Vacca, A. ; Ribatti, Doménico
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance between proinflammatory and anti-inflammatory cytokines, an imbalance between these inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis.
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Citation
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