Publication: Prostatic sequestration of Cryptococcus neoformans in immunocompromised persons treated for cryptococcal meningoencephalitis
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Date
1994
Authors
Ndimbie, O.K. ; Dekker, A. ; Martinez, A.J. ; Dixon, B.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
We report a case of a patient with acquired
immune deficiency syndrome who was successfully
treated for cryptococcal meningoencephalitis with
amphotericin B and 5-flucytosine. He died from other
sequelae of acquired immune deficiency syndrome two
years later. An autopsy revealed prominent cryptococcal
prostatitis. Cryptococci were neither found in the central
nervous system nor in other anatomic sites.
The autopsy files yielded seven other cases of men
with a history of cryptococcal meningoencephalitis. The
possibility that the prostate sequesters Cryptococcus
neoformans thereby contributing to systemic relapse is
explored. To qualify as a sequestration, cyptococci must
be cultured from the prostate, or from a midstream
voided specimen after prostatic massage, and the
prostate must be the only focus of infection.
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