Publication: Wnt signaling in kidney
tubulointerstitium during disease
Authors
Maarouf, Omar H. ; Ikeda, Yoichiro ; Humphreys, Benjamin D.
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Publisher
F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología
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DOI
https://doi.org/10.14670/HH-30.163
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info:eu-repo/semantics/article
Description
Abstract
The evolutionary conserved Wnt signaling
transduction pathway plays essential roles in a wide
array of biologic processes including embryonic
development, branching morphogenesis, proliferation
and carcinogenesis. Over the past ten years it has
become increasingly clear that Wnt signaling also
regulates the response of adult organs to disease
processes, including kidney disease. This review will
focus on the growing literature implicating important
roles for Wnt signaling during disease in two separate
kidney compartments: the tubular epithelium and the
interstitium.
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Citation
Histology and Histopathology, Vol. 30, n.º 2 (2015)
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