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Zinc finger proteins and regulation of the hallmarks of cancer

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dc.contributor.authorYe, Qin
dc.contributor.authorLiu, Jiayang
dc.contributor.authorXie, Ke
dc.date.accessioned2022-10-19T08:34:36Z
dc.date.available2022-10-19T08:34:36Z
dc.date.issued2019
dc.description.abstractZinc finger proteins (ZFPs) form one of the largest families of transcription factors in human genetics, via their conserved zinc finger motifs. ZFPs function in many biological processes including development, differentiation, metabolism and apoptosis. In addition, recent studies have demonstrated that ZFPs are closely associated with different stages of cancer development. One of the hallmarks of cancer is altered signal transduction cascades and an understanding of the changes in these pathways is essential for targeted cancer therapy. In this review, we discuss examples of ZFPs involved in development and progression of several types of cancer, which can provide new insights into cancer treatmentes
dc.formatapplication/pdfes
dc.format.extent13es
dc.identifier.citationHistology and Histopathology, Vol.34, nÂş10, (2019)
dc.identifier.doihttps://doi.org/10.14670/HH-18-121
dc.identifier.issn0213-3911
dc.identifier.issn1699-5848
dc.identifier.urihttp://hdl.handle.net/10201/124644
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectZinc finger proteinses
dc.subjectTranscription factorses
dc.subjectHallmarks of canceres
dc.subjectCancer therapyes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleZinc finger proteins and regulation of the hallmarks of canceres
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.34,nÂş10 (2019)