Regulation of EGFR endocytic trafficking by rab proteins

Publication:
Regulation of EGFR endocytic trafficking by rab proteins

dc.contributor.author	Ceresa, B.P.	es
dc.date.accessioned	2011-06-30T12:03:24Z
dc.date.available	2011-06-30T12:03:24Z
dc.date.issued	2006
dc.description.abstract	The Epidermal Growth Factor Receptor (EGFR) is a member of the receptor tyrosine kinase family and has important roles in development and cancer. Through ligand stimulation, the EGFR initiates a number of biochemical pathways that integrate to form specific physiological responses. In addition to these signaling pathways, the ligand stimulation also causes the EGFR to internalize and be transported through the endocytic pathway. The endocytic pathway regulates the rate of EGFR degradation and recycling, as well as the signaling mediated by the EGFR. In this review, the role of rabs, a family of small molecular weight guanine nucleotide binding proteins, is examined in how they regulate endocytic trafficking	es
dc.format	application/pdf	es
dc.format.extent	7	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/22694
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Rab	es
dc.subject	Growth factor receptor	es
dc.subject.other	CDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología	es
dc.title	Regulation of EGFR endocytic trafficking by rab proteins	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

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