Publication:
Morphometrical changes in the rat thymic lymphoid cells after treatment with two different doses of estradiol benzoate

Thumbnail Image
Files
Morphometrical changes in the rat thymic lymphoid cells after treatment with two different doses of estradiol benzoate.pdf(2.81 MB)
Date
1994
relationships.isAuthorOfPublication
relationships.isSecondaryAuthorOf
relationships.isDirectorOf
Authors
Martin, A. ; Alonso, L.M. ; Gomez del Moral, M. ; Zapata, A.G.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
In the present study we have evaluated morphometrically the contribution of thymocytes to the thymic involution induced by a single injection either of 100 pg or 500 pg of estradiol benzoate. Our results demonstrate that changes in the numbers of both cortical and medullary thymocytes contribute to thymic involution although the importance of the first is quantitatively higher. On the other hand, while cortical pyknosis and a decreased mitotic index could be important for explaining the estrogen-dependent thymic changes, the release of lymphocytes from thymus seems to be the main factor inducing the thymic involution as well as the lack of recovery observed at the end of the experimental period.
publication.page.subject
Thymus , Sex steroids
Citation
URI
http://hdl.handle.net/10201/18488
item.page.embargo
Collections
Histology and histopathology Vol. 9, nº 2 (1994)
Ir a Estadísticas