Publication:
The impact of calcium volume and distribution in aortic root injury related to balloon-expandable transcatheter aortic valve replacement

Simple item page
dc.contributor.authorHansson, Nicolaj C.
dc.contributor.authorNoorgaard, Bjarne L.
dc.contributor.authorBarbanti, Marco
dc.contributor.authorNielsen, Niels Erik
dc.contributor.authorYang, Tae-Hyun
dc.contributor.authorTamburino, Corrado
dc.contributor.authorDvir, Danny
dc.contributor.authorJilaihawi, Hasan
dc.contributor.authorBlanke, Phillip
dc.contributor.authorMakkar, Raj R.
dc.contributor.authorLatib, Azeem
dc.contributor.authorColombo, Antonio
dc.contributor.authorTarantini, Giuseppe
dc.contributor.authorRaju, Rekha
dc.contributor.authorWood, David
dc.contributor.authorAndersen, Henning R.
dc.contributor.authorRibeiro, Henrique B.
dc.contributor.authorKapadia, Samir
dc.contributor.authorMin, James
dc.contributor.authorFeuchtner, Gudrun
dc.contributor.authorGurvitch, Ronen
dc.contributor.authorAlqoofi, Faisal
dc.contributor.authorPelletier, Marc
dc.contributor.authorUssia, Gian Paolo
dc.contributor.authorNapodano, Massimo
dc.contributor.authorSandoli de Brito Jr., Fabio
dc.contributor.authorKodali, Susheel
dc.contributor.authorPache, Gregor
dc.contributor.authorCánovas López, Sergio
dc.contributor.authorBerger, Adam
dc.contributor.authorMurphy, Darra
dc.contributor.authorSvensson, Lars G.
dc.contributor.authorRodés Cabau, Josep
dc.contributor.authorLeon, Martin B.
dc.contributor.authorWebb, John G.
dc.contributor.authorLeipsic, Jonathon
dc.contributor.departmentCirugía, Pediatría y Obstetricia y Ginecología
dc.date.accessioned2024-07-19T10:31:24Z
dc.date.available2024-07-19T10:31:24Z
dc.date.issued2015-09
dc.descriptionCopyright © 2015 Society of Cardiovascular Computed Tomography. This document is the Published version of a Published Work that appeared in final form in Journal of Cardiovascular Computed Tomography. To access the final edited and published work see https://doi.org/10.1016/j.jcct.2015.04.002
dc.description.abstractBackground A detailed assessment of calcium within the aortic root may provide important additional information regarding the risk of aortic root injury during transcatheter heart valve replacement (TAVR). Objective We sought to delineate the effect of calcium volume and distribution on aortic root injury during TAVR. Methods Thirty-three patients experiencing aortic root injury during TAVR with a balloon-expandable valve were compared with a control group of 153 consecutive TAVR patients without aortic root injury (as assessed by post-TAVR multidetector CT). Using commercial software to analyze contrast-enhanced pre-TAVR CT scans, calcium volume was determined in 3 regions: (1) the overall left ventricular outflow tract (LVOT), extending 10 mm down from the aortic annulus plane; (2) the upper LVOT, extending 2 mm down from the annulus plane; and (3) the aortic valve region. Results Calcium volumes in the upper LVOT (median, 29 vs 0 mm3; P < .0001) and overall LVOT (median, 74 vs 3 mm3; P = .0001) were higher in patients who experienced aortic root injury compared with the control group. Calcium in the aortic valve region did not differ between groups. Upper LVOT calcium volume was more predictive of aortic root injury than overall LVOT calcium volume (area under receiver operating curve [AUC], 0.78; 95% confidence interval, 0.69–0.86 vs AUC, 0.71; 95% confidence interval, 0.62–0.82; P = .010). Upper LVOT calcium below the noncoronary cusp was significantly more predictive of aortic root injury compared to calcium underneath the right coronary cusp or the left coronary cusp (AUC, 0.81 vs 0.68 vs 0.64). Prosthesis oversizing >20% (likelihood ratio test, P = .028) and redilatation (likelihood ratio test, P = .015) improved prediction of aortic root injury by upper LVOT calcium volume. Conclusion Calcification of the LVOT, especially in the upper LVOT, located below the noncoronary cusp and extending from the annular region, is predictive of aortic root injury during TAVR with a balloon-expandable valve.es
dc.formatapplication/pdfes
dc.format.extent11es
dc.identifier.citationJournal of Cardiovascular Computed Tomography, 2015, Vol. 9, Issue 5, pp. 382-392
dc.identifier.doihttps://doi.org/10.1016/j.jcct.2015.04.002
dc.identifier.issnPrint: 1934-5925
dc.identifier.issnElectronic: 1876-861X
dc.identifier.urihttp://hdl.handle.net/10201/143261
dc.languageenges
dc.publisherElsevier
dc.relationSin financiación externa a la Universidades
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S1934592515001355#sec5
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAortic root calcificationes
dc.subjectAortic root injuryes
dc.subjectMultidetector computed tomographyes
dc.subjectTranscatheter aortic valve replacement
dc.titleThe impact of calcium volume and distribution in aortic root injury related to balloon-expandable transcatheter aortic valve replacementes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
1-s2.0-S1934592515001355-main.pdf
Size:
1.53 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.26 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Artículos