Publication: Adenomatous hyperplasia of the rete testis. A review and report of new cases
Authors
Nistal, M. ; Castillo, M.C. ; Regadera, J. ; García-Cabezas, M.A.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Adenomatous hyperplasia of the rete testis
(AHRT) is an uncommon benign lesion that
preferentially involves the septal rete testis and
mediastinal rete testis. It is usually an incidental finding
in surgical specimens from cryptorchidism and testicular
tumour. It can be found in autopsy specimens from
patients dying with different chronic diseases and
newborns with kidney diseases. Since its first description
many articles have been published communicating new
cases and putting forward some hypotheses on its
aetiology and pathogenic mechanisms. Some authors
suggest a role for hormonal changes, tumour invasion
and action of chemical agents. We think that AHRT
should be categorised into two main aetiological
categories: congenital and acquired. The cases
associated with different kidney and spermatic duct
diseases, most cases associated with cryptorchidic testis
and some cases associated with testicular germ cell
tumour should be included in the congenital group. The
remaining cases associated with chemical agents, some
hormonal changes (i.e. androgen blockade) and most of
the germ cell tumour cases can be considered as
acquired AHRT. Differential diagnosis must be
established mainly with metastatic adenocarcinoma of
prostate to testis and primary adenocarcinoma of the rete
testis. Pseudohyperplasia of the rete testis must also be
considered in atrophic testes. Here we review the papers
published on this subject and report our recent cases
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