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Effect of Pharmaceutical Intervention in Pharmacologically Treated Hypertensive Patients-A Cluster-Randomized Clinical Trial: AFPRES-CLM Study.

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dc.contributor.authorLuque Del Moral, Raúl
dc.contributor.authorGastelurrutia, Miguel A
dc.contributor.authorMartinez-Martinez, Fernando
dc.contributor.authorJacomé, Julio A
dc.contributor.authorDago, Ana
dc.contributor.authorSuarez, Blanca
dc.contributor.authorFikri-Benbrahim, Narjis
dc.contributor.authorMartí, Mercé
dc.contributor.authorNúñez Parra, Cristina
dc.contributor.authorSierra Alarcón, Sandra
dc.contributor.authorFernández Gómez, Francisco José
dc.contributor.departmentFarmacología
dc.date.accessioned2026-04-15T08:27:09Z
dc.date.available2026-04-15T08:27:09Z
dc.date.copyright© 2023 by the authors
dc.date.issued2023-10-11
dc.description.abstractBackground: Evaluate the effect of a community pharmaceutical intervention on the control of blood pressure in hypertensive patients treated pharmacologically. Methods: A cluster-randomized clinical trial of 6 months was carried out. It was conducted in the Autonomous Community of Castilla-La Mancha (Spain). Sixty-three community pharmacies and 347 patients completed the study. Intervention patients received the community pharmaceutical intervention based on a protocol that addresses the individual needs of each patient related to the control of their blood pressure, which included Health Education, Pharmacotherapy Follow-up and 24 h Ambulatory Blood Pressure Measurement. Control patients received usual care in the community pharmacy. Results: The pharmaceutical intervention resulted in better control of blood pressure (85.8% vs. 66.3% p < 0.001), lower use of emergencies (p = 0.002) and improvement trends in the physical components of quality of life, measured by SF-36 questionnaire, after 6 months of pharmaceutical intervention. No significant changes were observed for any of these variables in the control group. There were also detected 354 negative medication-related outcomes that were satisfactorily resolved in a 74.9% of the cases and 330 healthcare education interventions and 29 Ambulatory Blood Pressure Monitorings were performed in order to increase adherence to pharmacological treatment and minimize Negative Outcomes associated with Medication and prevent medication-related problems. Conclusions: Community pharmaceutical intervention can increase hypertensive patients with controlled blood pressure, after 6 months, compared with usual care.
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dc.format.extent13
dc.identifier.citationJ. Pers. Med. 2023, 13, 1484.
dc.identifier.doi10.3390/jpm13101484
dc.identifier.other37888095
dc.identifier.urihttp://hdl.handle.net/10201/225621
dc.languageeng
dc.language.isoen
dc.relationSin financiación externa a la Universidad
dc.relation.publisherversionhttps://www.mdpi.com/2075-4426/13/10/1484
dc.rightsAttribution 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectArterial hypertension
dc.subjectblood pressure control
dc.subjectcommunity pharmacy care program
dc.subjectOutcomes health
dc.subjectPharmaceutical intervention
dc.subject.odsObjetivo 3: Salud
dc.titleEffect of Pharmaceutical Intervention in Pharmacologically Treated Hypertensive Patients-A Cluster-Randomized Clinical Trial: AFPRES-CLM Study.
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublicationes
relation.isAuthorOfPublication353c85df-d611-4999-b8b7-960dd35d1011
relation.isAuthorOfPublication8024469c-32b7-4dfa-9993-0c9479575166
relation.isAuthorOfPublicationf84d0746-a2b3-4a19-9b93-78feb4f387b4
relation.isAuthorOfPublication.latestForDiscovery353c85df-d611-4999-b8b7-960dd35d1011
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