Publication: Killing two birds with one stone: The multifunctional roles of mesenchymal stem cells in the treatment of neurodegenerative and muscle diseases
Authors
Lee, Na Kyung ; Na, Duk L. ; Chang, Jong Wook
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Publisher
Universidad de Murcia. Departamento de Biología Celular e Histología
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DOI
DOI: 10.14670/HH-11-951
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info:eu-repo/semantics/article
Description
Abstract
Neurodegenerative and muscle diseases bear
both complex and multifactorial pathologies. An
efficacious and robust therapeutic option to treat these
diseases is yet to be elucidated. At such a time,
mesenchymal stem cells have drawn significant attention
due to their immunomodulatory and regenerative
properties. Accumulating evidence has proposed the
capability of MSCs to serve multiple roles in a broad
spectrum of diseases by secretion of trophic or paracrine
factors. In the present review, we will look into the
recent literature and discuss the therapeutic functions of
MSCs and their potential to treat various
neurodegenerative (Alzheimer’s, Parkinson’s, and
Huntington’s disease) and muscle (Duchenne muscular
dystrophy, myopathy, and multiple sclerosis) diseases.
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Citation
Histology and Histopathology, Vol.33, nº7, (2018)
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