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Presence of laminin and 67KDa laminin-receptor on endothelial surface of lung capillaries. An immunocytochemical study

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dc.contributor.authorHilario, E.es
dc.contributor.authorUnda, F.es
dc.contributor.authorPerez-Yarza, G.
dc.contributor.authorÁlvarez, A.
dc.contributor.authorGarcia-Sanz, M.
dc.contributor.authorAliño, S.F.
dc.date.accessioned2011-02-22T10:33:20Z
dc.date.available2011-02-22T10:33:20Z
dc.date.issued1996
dc.description.abstractThe existence of cell surface-associated molecules has been claimed to play a major role in cellular recognition and interaction. In this respect, different tumor cell lines express laminin and its receptor, and this expression has been correlated with metastatic potential. In the present work, we have studied, by electron microscopic immunolabeling methods, the presence of laminin and 67KDa lamininreceptor on the surface of endothelial cells of lung blood capillaries. To label these molecules, we have developed an easy method in which the labeling is carried out "in situ", in previously excised lungs. The presence of both molecules was observed on the luminal surface of endothelial capillaries and, in many cases, gold particles were associated to small open vesicles of the endothelial cells. The results suggest that these molecules, traditionally associated to extracellular matrix, are also expressed in cellular surface of the lung vascular bed.es
dc.formatapplication/pdfes
dc.format.extent4es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18878
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectEndotheliumes
dc.subjectLaminines
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titlePresence of laminin and 67KDa laminin-receptor on endothelial surface of lung capillaries. An immunocytochemical studyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.11, nº 4 (1996)