Environment, lifestyle behavior and health-related quality of life in childhood and adolescent cancer survivors of extracranial malignancies

Cárceles Álvarez, Alberto; Ortega García, Juan A.; López Hernández, Fernando A.; Fuster Soler, José L.; Sanz Monllor, Ainara; Ramis, Rebeca; Claudio, Luz

Publication:
Environment, lifestyle behavior and health-related quality of life in childhood and adolescent cancer survivors of extracranial malignancies

dc.contributor.author	Cárceles Álvarez, Alberto
dc.contributor.author	Ortega García, Juan A.
dc.contributor.author	López Hernández, Fernando A.
dc.contributor.author	Fuster Soler, José L.
dc.contributor.author	Sanz Monllor, Ainara
dc.contributor.author	Ramis, Rebeca
dc.contributor.author	Claudio, Luz
dc.contributor.department	Cirugía, Pediatría y Obstetricia y Ginecología
dc.date.accessioned	2024-02-06T11:42:44Z
dc.date.available	2024-02-06T11:42:44Z
dc.date.issued	2020-10
dc.description	©2020 Elsevier Inc. All rights reserved. This document is the Published Work that appeared in final form in Environmental Research. To access the final edited and published work see https://doi.org/10.1016/j.envres.2020.109910
dc.description.abstract	Background: Childhood cancer is a chronic disease with high survival rates. Childhood cancer survivors (CCS) can still face health effects later in their lives. Health-related quality of life (HRQoL) and the factors that modify it allow CCS and their families to improve care in the long-term follow-up. This study aims to: (1) examine the differences in HRQoL between CCS of extracranial malignancies and a comparison group, and (2) explore the clinical, environmental and lifestyles factors implicated in the HRQoL of CCS. Methods: In this cross-sectional study with a case vs. non-case comparison, the HRQoL of 117 CCS between 8 and 18 years old was compared with healthy non-cases paired by sex and age. The Pediatric Environmental History (PEHis) was applied to obtain information on sociodemographic, clinical, environmental and lifestyle factors. The PedsQL(TM) Generic Core Scales questionnaire was used to evaluate HRQoL. Results: In the multivariate analysis among the CCS, the following variables were significantly associated with HRQoL: Poor outdoor air quality (Total, Psychosocial, Emotional, Social and School domains); household income (Total, Psychosocial and School domains); and the presence of late effects (Total, Physical, Psychosocial, and Social domains); regular contact with nature (Physical domain); and the daily hours of screen-time (Emotional domain). CCS present HRQoL results superior to the non-cases group in the physical domain (86.10 vs. 80.34; p = 0.001), finding no differences in the other domains evaluated. Conclusions: An environmental and community health approach, such as PEHis, in CCS long-term programs promoting the creation of healthier environments and lifestyles contributes to improving their HRQoL and secondarily other chronic diseases.	es
dc.format	application/pdf	es
dc.identifier.citation	Environmental Research, 189, 2020, 109910
dc.identifier.doi	https://doi.org/10.1016/j.envres.2020.109910
dc.identifier.issn	0013-9351
dc.identifier.uri	http://hdl.handle.net/10201/138736
dc.language	eng	es
dc.publisher	Elsevier	es
dc.relation	This research was supported by the International Network of Environment, Survival and Childhood Cancer (ENSUCHICA) in Europe and Latin America (Fundación Formación e Investigación Sanitaria Región de Murcia, España, FIS EU17-01-01); the Mount Sinai International Exchange Program for Minority Students funded by the National Institute of Minority Health and Health Disparities (T37 MD001452); and the International Training and Research Program in Environmental and Occupational Health funded by the Fogarty International Center, United States (TW00640). The funders had no role in the completion of the research project, the writing of the manuscript for publication, or the decision to publish the results.	es
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/abs/pii/S0013935120308057	es
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject	Environmental health	es
dc.subject	Health-related quality of life	es
dc.subject	Cancer survivors	es
dc.subject	Lifestyles	es
dc.subject	Pediatric cancer	es
dc.title	Environment, lifestyle behavior and health-related quality of life in childhood and adolescent cancer survivors of extracranial malignancies	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es