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Association between Pulpal-Periapical Pathology and Autoimmune Diseases: A Systematic Review

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dc.contributor.authorGuerrero Gironés, Julia
dc.contributor.authorPecci Lloret, María Pilar
dc.contributor.authorRodríguez Lozano, Francisco Javier
dc.contributor.authorPecci Lloret, Miguel Ramón
dc.contributor.authorRos Valverde, Antonio
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned2022-04-23T22:10:25Z
dc.date.available2022-04-23T22:10:25Z
dc.date.issued2021
dc.description©<2021>. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by /4.0/ This document is the Published, version of a Published Work that appeared in final form in [Journal of Clinical Medicine]. To access the final edited and published work see[https://doi.org/10.3390/jcm10214886]
dc.description.abstractSeveral studies have linked apical periodontitis and systemic diseases. The aim of this study is to present a systematic review of the available literature investigating whether there is an association between pulpal-periapical pathology and autoimmune disease. The review was conducted following the PRISMA statement. A literature search was performed in five databases. Studies involving patients with pulpal-periapical pathology and autoimmune diseases were included in the review. Based on the PICO model, the research question aimed to assess whether there is an increased risk of developing pulpal-periapical pathology in patients with autoimmune disease. Article selection, data extraction, and quality assessment were performed using an adapted version of the STROBE guidelines. A total of seven studies were included in our review. The types of articles were five case-control and two cross-sectional studies. Periapical pathologies were associated to three autoimmune diseases (diabetes mellitus I, rheumatoid arthritis, and inflammatory bowel disease). Among the included studies, four show a low risk of bias, while three present a moderate risk. There could be an association between apical periodontitis and autoimmune diseases, although most studies report statistically non-significant associations.
dc.formatapplication/pdfes
dc.format.extent11
dc.identifier.citation10
dc.identifier.citationJournal of Clinical Medicine
dc.identifier.citationhttps://www.mdpi.com/journal/jcm
dc.identifier.doihttps://doi.org/10.3390/jcm10214886
dc.identifier.issn2077-0383
dc.identifier.urihttp://hdl.handle.net/10201/119063
dc.languageenges
dc.relation.isreferencedbyED_IDENTRADA=1011
dc.rightsinfo:eu-repo/semantics/openAccess*
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectapical periodontitis
dc.subjectirreversible pulpitis
dc.subjectautoimmune disease
dc.subjecttype I diabetes mellitus
dc.subjectrheumatoid arthritis
dc.subjectinflammatory bowel disease
dc.titleAssociation between Pulpal-Periapical Pathology and Autoimmune Diseases: A Systematic Reviewes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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