Accommodation-related changes in monochromatic aberrations of the human eye as a function of age

López Gil, Norberto; Fernández Sánchez, Vicente; Legras, Richard; Montés Micó, Robert; Lara Lacárcel, Francisco; Nguyen Khoa, Jean Luc

Publication:
Accommodation-related changes in monochromatic aberrations of the human eye as a function of age

dc.contributor.author	López Gil, Norberto
dc.contributor.author	Fernández Sánchez, Vicente
dc.contributor.author	Legras, Richard
dc.contributor.author	Montés Micó, Robert
dc.contributor.author	Lara Lacárcel, Francisco
dc.contributor.author	Nguyen Khoa, Jean Luc
dc.contributor.department	Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
dc.date.accessioned	2026-02-04T07:43:41Z
dc.date.available	2026-02-04T07:43:41Z
dc.date.copyright	© 2008, Association for Research in Vision and Ophthalmology
dc.date.issued	2008-04
dc.description.abstract	PURPOSE. To investigate the relationship between accommodation and the optical aberrations of the whole human eye, as a function of age. METHODS. Sixty healthy subjects with spherical ametropia in the range 3 D, astigmatism less than 1 D, corrected visual acuity of 20/18 or better, and normal findings in an ophthalmic examination were enrolled. Subjects were divided into four groups, with age ranges of 19 to 29, 30 to 39, 40 to 49, and 50 to 60 years. Monochromatic optical aberrations and pupil size were measured with a Hartmann-Shack wavefront sensor under monocular viewing conditions, without pharmacological dilation or cyloplegia. Stimulus vergences were in the range of 0 to 5 D, with an increment of 0.5 D. The change in aberration during accommodation for different groups and different pupil conditions (natural and fixed 4-mm pupil) was compared. RESULTS. Fourth-order spherical aberration (SA) became more negative with accommodation, and the rate of this change was greater in older individuals. For natural pupil conditions, there were no significant differences between age groups in the changes of the higher-order aberrations, coma, and trefoil with accommodation. However, for a 4-mm pupil, the youngest and oldest group showed significant differences in higher order RMS (root mean square) and spherical aberration compared with the other groups. High-order RMS showed a lower increase during accommodation when the pupil accommodative miosis was taken into account (natural pupil condition) than when a fixed 4-mm pupil was used. CONCLUSIONS. Aberrations change with accommodation and with age. SA changes more with accommodation do than other higher-order aberrations. SA becomes more negative with accommodation, and this change is larger in older individuals. Accommodative miosis is useful for ameliorating the increase in higher-order aberrations with accommodation.
dc.format	application/pdf
dc.format.extent	8
dc.identifier.citation	Invest Ophthalmol Vis Sci. 2008;49:1736–1743
dc.identifier.doi	https://doi.org/10.1167/iovs.06-0802
dc.identifier.eissn	1552-5783
dc.identifier.issn	0146-0404
dc.identifier.uri	http://hdl.handle.net/10201/198949
dc.language	eng
dc.publisher	Association for Research in Vision and Ophthalmology (ARVO)
dc.relation	Sin financiación externa a la Universidad
dc.relation.publisherversion	https://iovs.arvojournals.org/article.aspx?articleid=2184137
dc.rights	Attribution 4.0 International	*
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	*
dc.subject.ods	Objetivo 3: Salud
dc.title	Accommodation-related changes in monochromatic aberrations of the human eye as a function of age
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion
dspace.entity.type	Publication	es
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