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The cellular matrix: a feature of tensile bearing dense soft connective tissues

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dc.contributor.authorLo, I.K.es
dc.contributor.authorChi, S.es
dc.contributor.authorIvie, T.
dc.contributor.authorFrank, C.B.
dc.contributor.authorRattner, J.B.
dc.date.accessioned2011-05-11T10:58:05Z
dc.date.available2011-05-11T10:58:05Z
dc.date.issued2002
dc.description.abstractThe term connective tissue encompasses a d iverse group of tissues that reside in dif f e r e n t e nvironments and must support a spectrum of mechanical functions. Although the extracellular matrix of these tissues is well described, the cellular architecture of these tissues and its relationship to tissue function has only recently become the focus of study. It n ow appears that tensile-bearing dense connective tissues may be a specific class of connective tissues that display a common cellular organization characterized by fusiform cells with cytoplasmic projections and ga p junctions. These cells with their cellular projections are organised into a complex 3-dimensional network leading to a phy s i c a l l y, chemically and electrically connected cellular matrix. The cellular matrix may play essential roles in extracellular matrix formation, maintenance and remodelling, mechanotransduction and during injury and healing. Thus, it is likely that it is the interaction of both the extracellular matrix and cellular matrix that provides the basis for tissue function. Restoration of both these matrices, as well as their interaction must be the goal of strategies to repair these connective tissues damaged by either injury or disease.es
dc.formatapplication/pdfes
dc.format.extent15es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/20781
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectTendonsen_EN
dc.subjectLigamentsen_EN
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleThe cellular matrix: a feature of tensile bearing dense soft connective tissuesen_EN
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.17, nº 2 (2002)