Publication: Prognostic factors in renal cell carcinoma
Authors
Eker, Reidar ; Nesland, Jahn M. ; Andersen, Aage ; Johannessen, Jan Vicents
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
We studied 569 cases of renal cell carcinoma
in the file5 of the Department of Pathology of the
Nor~vegian Radium Hospital from 1964 to 1974. A
nephrectorny had been perfornied in all cases. Clinical
information on sex, age, survival time and metastases was
traced. The histological slides were examined and turnour
growth pattern, cell type, cell shape, nuclear atypia,
abnormal nucleoli, nuclear grade, va s c~~l ainrv asion and
tumour demarcation mere all evaluated.
Besides well-known prognostic factors j ~ ~ cash t uniour
stage, presence or absence of metastases and vascular
invasion, nuclear grade \sas found to be a useful prognostic
factor. Younger patients were found to do better than older,
and women better than men. Smaller tumours carried a
better prognosis than larger and clear cell turnours had a
better prognosis than those composed of eosinophilic or
basophilic cells. The presence of spindle cells was a bad
prognostic omen.
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