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Histological and immunohistochemical soft-tissue response to cylindrical and concave abutments: multicenter randomized clinical trial

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dc.contributor.authorCamacho Alonso, Fabio
dc.contributor.authorBernabeu Mira, Juan Carlos
dc.contributor.authorMercado Díaz, Ana María
dc.contributor.authorPérez Sayans, Mario
dc.contributor.authorPérez Jardón, Alba
dc.contributor.authorSomoza Martín, José Manuel
dc.contributor.authorMontero, Javier
dc.contributor.authorGómez Polo, Cristina
dc.contributor.authorQuispe López, Norberto
dc.contributor.authorPeñarrocha Oltra, David
dc.contributor.authorBuendía Marín, Antonio Julián
dc.contributor.authorSánchez Campillo, Joaquín
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned2024-11-15T11:11:54Z
dc.date.available2024-11-15T11:11:54Z
dc.date.issued2024-08-26
dc.description© 2024 The Author(s). This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published version of a Published Work that appeared in final form in Journal of Periodontology. To access the final edited and published work see https://doi.org/10.1002/JPER.24-0250es
dc.description.abstractBackground:This study aimed to analyze the influence of concave andcylindrical abutments on peri-implant soft tissue. Dimensions, collagen fiberorientation, and immunohistochemical data were assessed.Methods:A multicenter, split-mouth, double-blind randomized clinical trialwas conducted. Two groups were analyzed: cylindrical abutments and concaveabutments. After a 12-week healing period, peri-implant soft tissue samples werecollected, processed, and evaluated for dimensions, collagen fiber orientation,and immunohistochemical data. Inflammatory infiltration and vascularizationwere assessed, and the abutment surfaces were analyzed using scanning elec-tron microscopy. The statistical analysis was performed using the SPSS version20.0 statistical package.Results:A total of 74 samples in 37 patients were evaluated. Histologicalevaluation of peri-implant soft tissue dimensions revealed significant differ-encesbetweenconcaveandcylindricalabutments.Concaveabutmentsexhibitedgreater total height (concave: 3.57±0.28 – cylindrical: 2.95±0.27) and bar-rier epithelium extension (concave: 2.46±0.17 – cylindrical: 1.89±0.21)(p<0.05),whilethesupracrestalconnectivetissueextension(concave:1.11±0.17– cylindrical: 1.03±0.16) was slightly greater (p>0.05). Collagen fiber ori-entation favored concave abutments (23.76±5.86), with significantly moretransverse/perpendicular fibers than for cylindrical abutments (15.68±4.57).The immunohistochemical analysis evidenced greater inflammatory and vascu-lar intensity in the lower portion for both abutments, though concave abutmentsshowed lower overall intensity (concave: 1.05±0.78 – cylindrical: 1.97±0.68) (p<0.05). The abutment surface analysis demonstrated a higher percentage oftissue remnants on concave abutments (42.47±1.32; 45.12±3.03) (p<0.05).Conclusions:Within the limitations of this study, concave abutments pre-sented significantly greater peri-implant tissue height, linked to an extendedbarrier epithelium, versus cylindrical abutments in thick tissue phenotype.This enhanced soft tissue sealing, favoring a greater percentage of transverselyoriented collagen fibers. The concave design reduced chronic inflammatoryexudation with T and B cells, thus minimizing the risk of chronic inflammation.es
dc.formatapplication/pdfes
dc.format.extent11es
dc.identifier.citationJournal of Periodontology, 2024, Early View, pp. 1-11
dc.identifier.doihttps://doi.org/10.1002/JPER.24-0250
dc.identifier.issnPrint: 0022-3492
dc.identifier.issnElectronic: 1943-3670
dc.identifier.urihttp://hdl.handle.net/10201/146381
dc.languageenges
dc.publisherWileyes
dc.relationSin financiación externa a la Universidades
dc.relation.publisherversionhttps://aap.onlinelibrary.wiley.com/doi/10.1002/JPER.24-0250es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectDental implant abutment designes
dc.subjectDental implantses
dc.subjectHistologyes
dc.subjectImmunohistochemistryes
dc.subjectMulticenter studyes
dc.subjectOral surgical procedureses
dc.subjectRandomized controlled triales
dc.titleHistological and immunohistochemical soft-tissue response to cylindrical and concave abutments: multicenter randomized clinical triales
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
relation.isAuthorOfPublicationc084ce85-206c-418d-8cec-7f85a0f34dc0
relation.isAuthorOfPublication55adcadd-4bfb-42f2-9d70-37bd48550a78
relation.isAuthorOfPublication.latestForDiscoveryc084ce85-206c-418d-8cec-7f85a0f34dc0
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