Publication:
Gap junctions and expression of Cx36 Cx43 and Cx45 in the posterodorsal medial amygdala of adult rats

Simple item page
dc.contributor.authorZancan, Mariana
dc.contributor.authorMalysz, Tais
dc.contributor.authorMoura, Dinara J.
dc.contributor.authorMorás, Ana Moira
dc.contributor.authorSteffens, Luiza
dc.contributor.authorRasia-Filho, Alberto
dc.date.accessioned2022-11-15T10:05:52Z
dc.date.available2022-11-15T10:05:52Z
dc.date.issued2020
dc.description.abstractThe posterodorsal medial amygdala (MePD) has a synaptic organization that dynamically modulates reproduction and other social behaviors in rats. Discrete gap junctions between glial cells were previously reported in the MePD neuropil. Connexins (Cx) are components of gap junctions and indicative of cellular electrical coupling. Here, we report the ultrastructural occurrence of gap junctions between neurons in the MePD and demonstrate the expression and immunofluorescent labeling of Cx36, Cx43 and Cx45 in this subcortical area of adult male rats. Few neuronal gap junctions were found in the MePD and, when identified, occurred between dendrites. On the other hand, there is a diffuse presence and distribution of punctate labelling for the tested Cxs. Puncta were visualized isolated or forming clusters in the same focal plane of cell bodies or along the MePD neuropil. The Cx36 puncta were found in neurons, Cx43 in astrocytes and Cx45 in both neurons and astrocytes. Our data indicate the presence of few gap junctions and different Cxs composition in the MePD. Because Cxs can assemble, form hemichannel units and/or serve as transcriptional regulator, it is likely that additional modulation of intercellular communication can occur besides the chemical transmission in the MePD of adult rats.es
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.citationHistology and Histopathology Vol. 35, nº4 (2020)
dc.identifier.doihttps://doi.org/10.14670/HH-18-160
dc.identifier.issn0213-3911
dc.identifier.issn1699-5848
dc.identifier.urihttp://hdl.handle.net/10201/125603
dc.languageenges
dc.publisherUniversidad de Murcia, Departamento de Biologia Celular e Histiologiaes
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectExtended amygdalaes
dc.subjectConnexines
dc.subjectTransmission electron microscopyes
dc.subjectImmunofluorescencees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleGap junctions and expression of Cx36 Cx43 and Cx45 in the posterodorsal medial amygdala of adult ratses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Zancan-35-395-403-2020.pdf
Size:
2.81 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.39 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Histology and histopathology Vol.35, nº4 (2020)