Publication: PVAT: an important guardian of the cardiovascular system
Authors
Liang, Xiuying ; Qi, Yan ; Dai, Fan ; Gu, Jingya ; Yao, Wenjuan
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Publisher
Universidad de Murcia, Departamento de Biologia Celular e Histiologia
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DOI
https://doi.org/10.14670/HH-18-211
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info:eu-repo/semantics/article
Description
Abstract
Perivascular adipose tissue (PVAT) had long
been considered to serve only structural, vessel-
supporting purposes, but today PVAT is recognized to be
an endocrine organ with important physiological and
pathological effects. The expansion of PVAT in vascular
homeostasis and vascular disease has attracted much
interest. PVAT has been shown to release a wide
spectrum of molecules, such as PVAT-derived relaxing
factors (PVATRFs) and PVAT-derived contracting factors
(PVATCFs). PVAT dysfunction may lead to obesity,
atherosclerosis, and other cardiovascular diseases. This
review describes recent advances in our understanding
of PVAT’s important effects on the cardiovascular
system
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Citation
Histology and Histopathology Vol. 35, nº8 (2020)
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