Pd(II)-catalyzed deprotection of acetals and ketals containing acid sensitive functional groups

Juliá Hernández, Francisco; Arcas, Aurelia; Vicente, José

Publication:
Pd(II)-catalyzed deprotection of acetals and ketals containing acid sensitive functional groups

dc.contributor.author	Juliá Hernández, Francisco
dc.contributor.author	Arcas, Aurelia
dc.contributor.author	Vicente, José
dc.contributor.department	Química Inorgánica
dc.date.accessioned	2025-01-07T11:38:19Z
dc.date.available	2025-01-07T11:38:19Z
dc.date.issued	2014-02-05
dc.description	© 2014. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/.This document is the Accepted version of a Published Work that appeared in final form in Tetrahedron Letters. To access the final edited and published work see https://doi.org/10.1016/j.tetlet.2013.12.067
dc.description.abstract	The pincer complex [Pd(C1,O1,N1-L)(NCMe)]ClO4 (L = monoanionic ligand resulting from deprotonation of the acetyl group of the dimethyl monoketal of 2,6-diacetylpyridine) is used for the high-yield and selective catalytic hydrolysis of aliphatic, aromatic, cyclic and acyclic dimethyl-acetals, - ketals and dioxolanes, even in the presence of large substituents. Other protecting groups, as THP or TBDMS, or very acid-sensitive alcohols were not affected. The catalyst is easily prepared in high yield from Pd(AcO)2 and 2,6-diacetylpyridinium perchlorate stable to air and moisture, easily and fully recoverable and reusable.
dc.format	application/pdf	es
dc.format.extent	13	es
dc.identifier.citation	Tetrahedron Letters 2014, 55, 1141-1144
dc.identifier.doi	https://doi.org/10.1016/j.tetlet.2013.12.067
dc.identifier.issn	Print: 0040-4039
dc.identifier.issn	Electronic: 1873-3581
dc.identifier.uri	http://hdl.handle.net/10201/147930
dc.language	eng	es
dc.publisher	Elsevier
dc.relation	Ministerio de Educación y Ciencia (Spain), FEDER (Grant CTQ2011-24016) and Fundación Séneca (Grants 04539/GERM/06 and 03059/PI/05) for financial support and a grant to F. J.-H.	es
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S0040403913021539?via%3Dihub
dc.rights	info:eu-repo/semantics/openAccess	es
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Acetals	es
dc.subject	Catalysis	es
dc.subject	Hydrolysis	es
dc.subject	Palladium	es
dc.subject	Acetal deprotection	es
dc.subject.other	CDU::5 - Ciencias puras y naturales	es
dc.title	Pd(II)-catalyzed deprotection of acetals and ketals containing acid sensitive functional groups	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es