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Linkage between cell membrane proteins and actin-based cytoskeleton the cytoskeletal-driven cellular functions

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dc.contributor.authorFais, S.es
dc.contributor.authorLuciani, F.es
dc.contributor.authorLogoui, M.
dc.contributor.authorParlato, S.
dc.contributor.authorLozupone, F.
dc.date.accessioned2011-02-22T11:21:37Z
dc.date.available2011-02-22T11:21:37Z
dc.date.issued2000
dc.description.abstractAsymmetric organization of the plasma membrane and cytosolic organelles is fundamental for a variety of cells, including bacteria, yeast and eukaryotic cells (Nelson, 1992). The degree into which cells polarize is characterized by their ability to create and maintain morphologically and biochemically distinct plasma membrane domains. The generation and maintenance of polarized distribution of membrane components (proteins and lipids) is thus critical to the ability of cells to perform complex activities such as cell-to-cell interactions, vectorial transport and secretion, cellular immunity, development and morphogenesis. Modification of cellular polarity may potentially lead to abnormal cellular activities and various pathological disorders (Molitoris, 1991; Carone et al., 1994; Chen et al., 1995). Our review shows the complex interplay between membrane proteins and the cytoskeletal network in determining the "polarized phenotype" in the cell. We provide evidence that membrane/cytoskeleton interaction is the key to regulation of the vast majority of cellular functions.es
dc.formatapplication/pdfes
dc.format.extent11es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/19327
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectCytoskeletones
dc.subjectMembranees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleLinkage between cell membrane proteins and actin-based cytoskeleton the cytoskeletal-driven cellular functionses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.15, nº 2 (2000)