Publication: Neuron specific enolase-positive breast carcinomas
Authors
Erikstein, Bjerrn ; Nesland, Jahn M. ; Ottestad, Lars ; Lund, Eiliv ; Johannessen, Jan Vicents
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Ninety-eight patients treated for breast
carcinomas were followed from 54 to 75 months after
primary diagnosis. All had undergone a modified radical
mastectomy with removal of axillary lymph nodes.
36 breast carcinomas were NSE-positive and 62 were
negative. NSE-positive tumours were significantly more
frequently estrogen receptor-positive than the NSEnegative
tumours, and the estrogen receptor values were
higher in the NSE-positive groups.
Patients with NSE-positive tumours and patients with
NSE-negative tumours did not differ with regard to
presence of lymph node metastases at the time of
primary surgery. However, the study showed that
patients with NSE-positive tumours had a tendency
towards more lymph node metastases after primary
surgical intervention, but a better outcome than patients
with NSE-negative tumours and metastases.
This study, with a 5-year follow up, failed to
demonstrate any major prognostic significance of
immunostaining for NSE.
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Citation
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