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Eccrine spiradenoma of the nipple: Case report, differential diagnosis and literature review

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dc.contributor.authorMetovic, Jasna
dc.contributor.authorGallino, Chiara
dc.contributor.authorZanon, Eugenio
dc.contributor.authorBussone, Riccardo
dc.contributor.authorRusso, Roberto
dc.contributor.authorVissio, Elena
dc.contributor.authorAnnaratone, Laura
dc.contributor.authorConti, Luca
dc.contributor.authorPapotti, Mauro
dc.contributor.authorCassoni, Paola
dc.contributor.authorCastellano, Isabella
dc.date.accessioned2022-07-07T07:33:40Z
dc.date.available2022-07-07T07:33:40Z
dc.date.issued2019
dc.description.abstractEccrine spiradenoma is a rare lesion originating from eccrine sweat glands, with only few cases reported in breast tissue: we here describe for the first time, an eccrine spiradenoma arising in the nipple. An 84 year-old woman with a lesion enlarging her right nipple, showing ulcerations and eczema-like changes of the covering skin, was admitted to our hospital. Surgical excision of the central quadrant with nipple-areola complex was performed, followed by histopathological evaluation which revealed an adenoma with predominantly basaloid epithelial cells. The lesion was composed of tightly packed small and large groups of cells, arranged in diffuse alveolar/pseudorosette formations. The small cells expressed p63 and calponin, while a positive expression of CK7 and CD117 was detected in large cells. After careful and detailed examination, excluding various similar entities, a diagnosis of eccrine spiradenoma has been rendered. Although extremely rare, eccrine spiradenoma should be taken into account in the differential diagnosis of subcutaneous primary breast tumors.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.citationHistology and Histopathology, Vol.34, nÂş8, (2019)
dc.identifier.doiDOI: 10.14670/HH-18-094
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/122183
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectEccrine spiradenomaes
dc.subjectBreastes
dc.subjectNipple-areola complexes
dc.subjectPitfallses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleEccrine spiradenoma of the nipple: Case report, differential diagnosis and literature reviewes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.34, nÂş8 (2019)