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Ultrastructural study of the vascular response in small early gastric cancer

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dc.contributor.authorCaruso, R.A.es
dc.contributor.authorCicciarello, R.es
dc.contributor.authorD'Aquino, Alessandra
dc.contributor.authorInferrera, C.
dc.date.accessioned2011-02-22T10:31:41Z
dc.date.available2011-02-22T10:31:41Z
dc.date.issued1996
dc.description.abstractThe microvasculature of the stroma of four cases of small early gastric cancer (EGC) was investigated by conventional electron microscopy. Severe damage to small and large fenestrated capillaries was observed around endothelium-adherent, partially degranulated neutrophils. The findings suggest the existence of neutrophil-mediated injury of endothelial cells during the development of inflammatory responses in small EGC. The severely injured microvessels exhibited increase in vasopermeability, microhaemorrhage, and platelet aggregates. Other microvascular changes included endothelial cell and pericyte activation as well as basal lamina replications, indicative of repeated episodes of endothelial injury, necrosis and regeneration. This new capillary growth within the old basal laminas shared morphological features with a peculiar angiogenic process described in man and animals.es
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18807
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectSmall early gastric canceres
dc.subjectTumour microvasculature changeses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.3 - Patología del aparato digestivo. Odontologíaes
dc.titleUltrastructural study of the vascular response in small early gastric canceres
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.11, nº 1 (1996)