Publication: Morphometric study of the LH-immunoreactive gonadotrophic cells of rats following treatment
with methoclopramide
Authors
Carretero, J. ; Sánchez, F. ; Montero, M. ; González, R. ; Blanco, E. ; Riesco, J. M. ; Vázquez, R.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The LH-immunoreactive cells of the adult rat
hypophysis were studied morphometrically after chronic
treatment with methoclopramide. The morphological
features of these cells showed modifications in both male
and female rats, after treatment. Additionally, morphometric
changes revealed a significant decrease (p < 0.05)
in both cytoplasmic area, which was more evident in the
female rats, and nuclear area, with respect to the normal
and control animals. These findings suggest that chronic
inhibition of the dopaminergic system in rats atrophies
LH-immunoreactive gonadotrophic cells of rats.
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Citation
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