Effect of a chronotype-adjusted diet on weight loss effectiveness:  a randomized clinical trial

Galindo Muñoz, J.S.; Díaz Soler, I.; Barberá Ortega, M.C.; Martínez Cáceres, J.J.; Hernández Morante, Juan José; Gómez Gallego, María

Publication:
Effect of a chronotype-adjusted diet on weight loss effectiveness: a randomized clinical trial

dc.contributor.author	Galindo Muñoz, J.S.
dc.contributor.author	Díaz Soler, I.
dc.contributor.author	Barberá Ortega, M.C.
dc.contributor.author	Martínez Cáceres, J.J.
dc.contributor.author	Hernández Morante, Juan José
dc.contributor.author	Gómez Gallego, María
dc.contributor.department	Atención Sociosanitaria
dc.date.accessioned	2024-09-18T07:59:19Z
dc.date.available	2024-09-18T07:59:19Z
dc.date.issued	2020-04
dc.description	© 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. This document is the Published version of a Published Work that appeared in final form in Clinical Nutrition. To access the final edited and published work see https://doi.org/10.1016/j.clnu.2019.05.012
dc.description.abstract	Background & aims: The alteration of normal biological rhythms, also known as chronodisruption, may be associated with obesity development. For instance, those subject with preference for vespertinity seem to be prone to develop obesity. However, the current hypocaloric dietary treatment of obesity does not take into account these aspects. Therefore, the objective of this trial was to evaluate whether a diet adjusted to patient's chronotype is more effective that the current dietary recommendations. Methods: 209 subjects take part on a 3 month randomized, double-blind trial. 104 subjects followed a typical hypocaloric dietary treatment and the other 105 subjects undergone a diet with a daily caloric distribution adjusted to their chronotype. There were no sex or age differences between groups. Results: Baseline characteristics were similar in both groups. Dropout rate was also similar in both in terventions (p ¼ 0.683). Although both groups improved their anthropometrical parameters, the chronotype-adjusted diet group achieved a statistically significant greater reduction in percentage of total body weight loss (%TWL), BMI and waist circumference than the control group (p < 0.010 in all contrasts). The effect on clinical parameters was less pronounced. Conclusions: This randomized trial has demonstrated for the first time that in overweight/obese subjects, a chronotype-adjusted diet is more effective than the traditional hypocaloric dietary treatment, at least regarding the anthropometrical parameters. Further research will confirm if this intervention is also more effective in the long term.	es
dc.format	application/pdf	es
dc.format.extent	8	es
dc.identifier.citation	Clinical Nutrition, 2020, Vol. 39, N. 4, pp. 1041 - 1048
dc.identifier.doi	https://doi.org/10.1016/j.clnu.2019.05.012
dc.identifier.issn	Electronic: 1532-1983
dc.identifier.issn	Print: 0261-5614
dc.identifier.uri	http://hdl.handle.net/10201/144040
dc.language	eng	es
dc.publisher	Elsevier	es
dc.relation	PMAFI/14/12 project, from the Support for Research Help Program of the Catholic University of Murcia.	es
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S0261561419302237
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject	Choronotype	es
dc.subject	Obesity	es
dc.subject	Hypocaloric diet	es
dc.subject	Randomized clinical trial	es
dc.title	Effect of a chronotype-adjusted diet on weight loss effectiveness: a randomized clinical trial	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es
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relation.isAuthorOfPublication.latestForDiscovery	44278cfb-f559-47b0-950d-fdecaf73adf3