Publication: Melanization stimulating factors in the integument of the Mugil cephalus and Dicertranchus labrax
Loading...
Date
2000
Authors
Zuasti, A. ; Martínez Liarte, José Hilario ; Solano, F. ; Ferrer, C.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
The pigment pattern expression resides in the
chromatoblasts of the embryonic skin. The
differentiation of these chromatoblasts is influenced by
specific local factors such a melanization inhibiting
factor (MIF) and a melanization-stimulating factor
(MSF). We reveal the presence of these factors by means
of a series of experiments on the skin of the marine
species of fish Dicertranchus labrax and Mugil
cephalus, each with different pigment pattern, the former
having a light skin and the latter a darker one. Media
conditioned by exposure to dorsal andtor ventral skin,
stimulates the melanization of Xenopus laevis neural
crest cells throughout a 3 day assay period. Similarly
conditioned culture media tested on B16-F10 murine
malignant melanocytes, revealed a considerable
influence in enzymatic activities: dopachrome
tautomerase (DCT), tyrosine hydroxylase and dopa
oxidase. The use of media in a dose response basis
suggests that the conditioned media may contain both
melanophore stimulating and inhibiting factors. The
results obtained may actually reflect the resultant
activity of the two factors present.
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.