Publication: Cellular localization of insulin-like growth factor-II protein in the sea bass -Dicentrarchus labrax- from hatching to adult
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Date
2008
Authors
Radaelli, G. ; Poltronieri, C. ; Bertotto, D. ; Funkenstein, B. ; Simontacchi, C.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The cellular localization of IGF-II protein
was investigated during larval and postlarval
developmental stages of sea bass (Dicentrarchus labrax)
by immunohistochemistry using antisera raised against
Sparus aurata IGF-II. At hatching, IGF-II
immunoreactivity was already present in the skin,
developing intestine and skeletal muscle. During larval
life IGF-II protein was also observed in heart
musculature, in kidney and gill epithelia as well as in
liver. In fry skeletal muscle a moderate IGF-II
immunostaining was detected in red fibres, whereas
white muscle fibres exhibited a faint immunoreactivity.
In adults, a marked IGF-II immunostaining was
observed in red muscle fibres. A moderate
immunoreactivity was also present in white fibres as
well as in heart striated myocardial fibres. These results
are in agreement with previous findings on the spatial
localization of IGF-II and IGF type 1 receptor in S.
aurata and Umbrina cirrosa, confirming the role of IGF
system during development and growth of fish.
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