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IQGAP1: A microtubule-microfilament scaffolding protein with multiple roles in nerve cell development and synaptic plasticity

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dc.contributor.authorJausoro, Ignacio
dc.contributor.authorMestres, Iván
dc.contributor.authorRemedi, Mónica
dc.contributor.authorSanchez, Mónica
dc.contributor.authorCáceres, Alfredo
dc.date.accessioned2017-11-07T15:54:20Z
dc.date.available2017-11-07T15:54:20Z
dc.date.issued2012
dc.description.abstractIn this article, we review our current understanding of the biology of IQ domain-containing GTPase-Activating Protein 1, IQGAP1, a scaffolding protein with multiple binding partners, which is widely expressed among different cell types, including neurons, and capable of linking Rho-GTPase signaling with cytosleletal elements and environmental cues. Interestingly, a series of recent studies suggest that IQGAP family members have an important role in neuronal development, synaptic plasticity and nervo system disorders involving alterations in spine density.es
dc.formatapplication/pdfes
dc.format.extent10es
dc.identifier.citationHistology and histopathology, Vol. 27, n.º 11 (2012)
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/54444
dc.languageenges
dc.publisherF. Hernández y Juan F. Madrid. Universidad de Murcia. Departamento de Biología Celular e Histologíaes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectIQGAP1es
dc.subjectSignalinges
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::612 - Fisiologíaes
dc.titleIQGAP1: A microtubule-microfilament scaffolding protein with multiple roles in nerve cell development and synaptic plasticityes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.27, nº11 (2012)