Study of different reaction schemes for the enzymatic synthesis of polyglycerol polyricinoleate

Ortega Requena, Salvadora; Gómez, J.L.; Máximo Martín, María Fuensanta; Montiel Morte, María Claudia; Murcia Almagro, María Dolores

Publication:
Study of different reaction schemes for the enzymatic synthesis of polyglycerol polyricinoleate

dc.contributor.author	Ortega Requena, Salvadora
dc.contributor.author	Gómez, J.L.
dc.contributor.author	Máximo Martín, María Fuensanta
dc.contributor.author	Montiel Morte, María Claudia
dc.contributor.author	Murcia Almagro, María Dolores
dc.contributor.department	Ingeniería Química
dc.date.accessioned	2021-10-21T09:30:13Z
dc.date.available	2021-10-21T09:30:13Z
dc.date.issued	2014-01-08
dc.description.abstract	BACKGROUND Different strategies for the solvent-free enzymatic production of polyglycerol polyricinoleate (PGPR) were explored in an attempt to simplify and improve the process. Besides the conventional procedure (obtaining polyricinoleic acid, followed by its esterification with polyglycerol), two alternative methods are proposed: (1) reversing the synthesis order, i.e. esterification of polyglycerol with ricinoleic acid and then the condensation of ricinoleic acid with the previously obtained polyglycerol ester; and (2) the enzymatic synthesis of PGPR in a single-step process. RESULTS The reaction sequences were carried out in an open-air reactor with free and immobilised lipases (triacylglycerol acylhydrolases, E.C. 3.1.1.3): Candida rugosa lipase to obtain polyricinoleic acid and Rhizopus oryzae lipase for the esterification of polyglycerol with the carboxyl group of ricinoleic or polyricinoleic acid. A co-immobilised derivative containing both lipases was used to catalyse the single-stage scheme. The three processes were carried out in a vacuum reactor, obtaining in every case PGPR that complied with the legal specifications of the European Community and recommendations provided in the Food Chemical Codex. CONCLUSION The results demonstrate that all three protocols are viable for the enzymatic synthesis of PGPR and require similar reaction times. The single-stage scheme is easier to carry out. © 2014 Society of Chemical Industry	es
dc.format	application/pdf	es
dc.format.extent	43	es
dc.identifier.doi	https://doi.org/10.1002/jsfa.6559
dc.identifier.uri	http://hdl.handle.net/10201/113148
dc.language	eng	es
dc.relation	Ámbito del proyecto (Europeo, nacional o regional): Nacional Agencia/entidad financiadora: Ministerio de Ciencia e Innovación Convocatoria: Nombre del proyecto: Biosíntesis de emulsionantes con aplicaciones alimentarias y cosmeticas, en sistemas solvent free, utilizando lipasas comerciales. Código: CTQ2011-24091	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.title	Study of different reaction schemes for the enzymatic synthesis of polyglycerol polyricinoleate	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es