Publication: Beyond Precision: Ambiomic Survivorship in Childhood and AYA Cancer
| dc.contributor.author | Ortega García, Juan Antonio | |
| dc.contributor.author | Shakeel, Omar | |
| dc.contributor.author | Wood, Nicole M. | |
| dc.contributor.author | Pérez-Martínez, Antonio | |
| dc.contributor.author | Fuster Soler, José Luis | |
| dc.contributor.author | Miller, Mark D. | |
| dc.contributor.department | Cirugía, Pediatría y Obstetricia y Ginecología | |
| dc.contributor.other | Facultades de la UMU::Facultad de Medicina | |
| dc.date.accessioned | 2026-05-20T07:13:48Z | |
| dc.date.available | 2026-05-20T07:13:48Z | |
| dc.date.copyright | © 2025 by the authors. | |
| dc.date.issued | 2026 | |
| dc.description.abstract | Revisión narrativa que propone un modelo ambiómico de supervivencia en cáncer infantil y del adolescente y adulto joven, desplazando el seguimiento desde la vigilancia postratamiento hacia una atención anticipatoria iniciada en el diagnóstico. El artículo integra marcos internacionales de supervivencia —COG, IGHG, PanCare y NCCN— con evidencia sobre determinantes ambientales, exposoma, toxicogenómica, salud pública e implementación clínica. A partir de la experiencia de la Historia Clínica Ambiental Pediátrica y del programa PLASESCAP-MUR de Murcia, describe la evolución hacia el Ambiomic Health Compass, incorporando evaluación ambiental y social estructurada, Green Page, Green Passport, biomonitorización, datos geoespaciales y alertas dinámicas. El modelo PEHis–AHC se plantea como una referencia escalable para integrar salud ambiental en oncología pediátrica, reducir eventos prevenibles y mortalidad relacionada con el tratamiento, mejorar la equidad y reforzar la continuidad asistencial desde el diagnóstico y a lo largo de la supervivencia. | |
| dc.format | application/pdf | |
| dc.format.extent | 23 | |
| dc.identifier.citation | Ortega-García, J. A., Shakeel, O., Wood, N. M., Pérez-Martínez, A., Fuster-Soler, J. L., & Miller, M. D. (2026). Beyond Precision: Ambiomic Survivorship in Childhood and AYA Cancer. Cancers, 18(1), 7. https://doi.org/10.3390/cancers18010007 | |
| dc.identifier.doi | https://doi.org/10.3390/cancers18010007 | |
| dc.identifier.eissn | 2072-6694 | |
| dc.identifier.uri | http://hdl.handle.net/10201/233161 | |
| dc.language | eng | |
| dc.publisher | MDPI | |
| dc.relation | This work was supported by the Asociación Pablo Ugarte, through a grant to the Pediatric Environmental Health Research Group at the Instituto Murciano de Investigación Biosanitaria IMIB– “Pascual Parrilla” (Murcia, Spain). Funding was provided within the Guardianes de Salud Planetaria (“Planetary Health Guardians”) initiative, a PEHis–AHC–based program aimed at reducing treatmentrelated mortality in children with cancer and at developing ambiomic precision tools for survivorship care. Work on this paper by Drs. Wood and Miller was supported by cooperative agreement FAIN: NU61TS000356 from the Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry (CDC/ATSDR) totaling $8,724,963.00 with 75% funded by CDC/ATSDR. The U.S. Environmental Protection Agency (EPA) provided the remaining support through Inter-Agency Agreement 24TSS2400078 with CDC/ATSDR. | |
| dc.relation.publisherversion | https://www.mdpi.com/2072-6694/18/1/7 | |
| dc.rights | Attribution 4.0 International | * |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
| dc.subject | Survivorship care model | |
| dc.subject | AYA oncology | |
| dc.subject | Exposome | |
| dc.subject | Ambiomic medicine | |
| dc.subject | Environmental health | |
| dc.subject | Late effects | |
| dc.subject | Chronic diseases | |
| dc.subject | Equity | |
| dc.subject | Pediatric cancer | |
| dc.subject.ods | Objetivo 3: Salud | |
| dc.title | Beyond Precision: Ambiomic Survivorship in Childhood and AYA Cancer | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication | es |
| relation.isAuthorOfPublication | 625b99b7-d25c-49eb-b53c-f389378e6993 | |
| relation.isAuthorOfPublication | 8ddf4081-7464-4475-8d28-d11ae9829e34 | |
| relation.isAuthorOfPublication.latestForDiscovery | 625b99b7-d25c-49eb-b53c-f389378e6993 |
Collections
Este ítem está sujeto a una licencia Creative Commons. http://creativecommons.org/licenses/by/4.0/