Publication: Scanning electron microscopic and light microscopic observations on morphological changes of freeze-dried bone implantation in rats
Loading...
Date
1992
Authors
Matsuda, Mikio ; Satoh, Y. ; Ono, K.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
Bone remodelling after the implantation of
freeze-dried autogenous bone in rat parietal bone was
compared with fresh autogenous bone transplantation,
using a scanning electron and light microscope revealed
the time intervals after transplantationfimplantation. The
light microscope revealed the time delay of the bone
remodelling in the implantation, compared with the
transplantations. The scanning electron microscope
showed that the differences between the two groups were
in the states of bone union and bone resorption. In the
fresh bone group, the newly-formed bone filled the
spaces between host and the transplanted bones at 2 to 3
weeks after the transplantation: the newly-formed bone
fused and melted into the transplanted bone. New bone
formation was more dominant on the bone surface in the
dura mater side than in the skin side. The union was
almost completed at 5 weeks. In freeze-dried bone
implantation, the bone union in the contact space was
very poor and the implanted bone was mainly covered by
the new bone, which developed from the host bone
surface in the dura mater side at 2 to 3 weeks after the
implantation. What is noteworthy is that bone resorbed
areas showing numerous Howship's lacunae were mainly
observed on the host bone surface in the vicinity of
newly-formed bone. However in freeze-dried bone
implantation, the bone resorption was greater on the host
and implanted bone surface than that of fresh bone
transplantation: the resorption of host bone was
considerably larger at certain periods after freeze-dried
bone implantation. The present results show that the
healing process of freeze-dried bone implantation, even
though autogenous bone was used, differed from that of
fresh autogenous bone transplantation, and the differences
are concerned not only with time sequences but also with
qualitative changes. This suggests that the host would
have some different responses to the freeze-dried
autogenous bone from fresh materials.
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.