Publication: Lectin histochemistry of mixed gliomas demonstrating an intermediate cell type
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Date
1998
Authors
Schill, J. ; Cervós-Navarro, J.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
18 cases oí' low-graded rnixed gliornas were
studied using the two lectins Concanavalin A (Con A)
and Peanut lectin (PNA). Con A stained cytoplasm and
processes of turnoral astrocytes, whereas PNA stained
cell membranes of tumoral oligodendrocytes. Con A and
PNA are reliable markers for astrocyte and oligodendrocyte
areas of mixed gliornas, respectively. A part of cells
were overlappingly positive for both lectins. They
expressed an oligosaccharide pattern of both gliorna
types and represented a third, interrnediate cell type of
rnixed gliomas. The existence of interrnediate cells close
to astrocytic and oligodendroglial cell types in mixed
gliomas could result frorn transformation processes of
neoplastic glial cells or frorn the malignant transformation
of a common glial precursor cell.
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