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Advances of MUC1 as a target for breast cancer immunotherapy

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Advances of MUC1 as a target for breast cancer immunotherapy.pdf(378.3 KB)
Date
2007
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Authors
Yang, E. ; Hu, X.F. ; Xing, P.X.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
MUC1 is a potential target in breast cancer immunotherapy as MUC1 is overexpressed in breast cancer, and is absent or expressed in low level in normal mammary gland. In addition, MUC1 is mostly aberrantly underglycosylated in cancer and the antigens on the cancer surface are different from normal cell. Therefore targeting MUC1 for cancer immunotherapy can exploit the difference between cancer and normal cells, and eliminating the cancerous cells while leaving the normal mammary cells unharmed. This review will focus on the recent advance of MUC1 breast cancer immunotherapy currently being investigated.
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Immunotherapy , Breast cancer
Citation
URI
http://hdl.handle.net/10201/27626
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Histology and histopathology Vol.22, nº 8 (2007)
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