Endosome-to-Golgi transport
pathways in physiological processes

Zhao Lieu, Zi; Gleeson, Paul A.

Publication:
Endosome-to-Golgi transport pathways in physiological processes

dc.contributor.author	Zhao Lieu, Zi
dc.contributor.author	Gleeson, Paul A.
dc.date.accessioned	2016-03-09T15:39:23Z
dc.date.available	2016-03-09T15:39:23Z
dc.date.issued	2011
dc.description.abstract	The trans-Golgi network (TGN) is a major traffic hub of the cell, as it regulates membrane transport in the secretory pathway as well as receiving protein cargo by retrograde transport from endocytic compartments. Retrograde transport between endosomes and the TGN is essential for the recycling of membrane proteins which regulate a range of cellular and development functions. In addition, retrograde transport pathways are exploited by many bacterial toxins to mediate cytotoxicity and by some viral proteins to promote pathogenicity. Recent advances using a range of molecular cell biological strategies have identified multiple retrograde transport pathways each regulated by a distinct set of molecular machinery. Here we review recent advances in this field and highlight the importance of these transport pathways in a range of physiological processes.	es
dc.format	application/pdf	es
dc.format.extent	14	es
dc.identifier.issn	1699-5848
dc.identifier.issn	0213-3911
dc.identifier.uri	http://hdl.handle.net/10201/48289
dc.language	eng	es
dc.publisher	Murcia: F. Hernández	es
dc.relation.ispartof	Histology and histopathology, Vol. 26, nº 3 (2011)	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Endosome	es
dc.subject	Golgins	es
dc.subject.other	577 - Bioquímica. Biología molecular. Biofísica	es
dc.title	Endosome-to-Golgi transport pathways in physiological processes	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es